Ficha bronchial asthma

Área de especialidad: Ciencias Biológicas, Químicas y de la Salud
Disciplina: Médico Cirujano
 Temática: Neumología

 Definición
A medical condition which causes the airway path of the lungs to swell and narrow and, due to this swelling, the air path produces excess mucus making it hard to breathe, which results in coughing, short breath, and wheezing.

 Fuente / Autor
The Respiratory System. (2022). Lungs: Definition, Location, Anatomy, Function, Diagram. Recuperado el 07 de abril de 2022, de https://www.therespiratorysystem.com/lungs/

 Contexto del término
Asthma is a complex disease with a variable course. Efforts to identify biomarkers to predict asthma severity, the course of disease and response to treatment have not been very successful so far. Biomarker research has expanded greatly with the advancement of molecular research techniques. An ideal biomarker should be suitable to identify the disease as well the specific endotype/phenotype, useful in the monitoring of the disease and to determine the prognosis, easily to obtain with minimum discomfort or risk to the patient. An ideal biomarker should be suitable to identify the disease as well the specific endotype/phenotype, useful in the monitoring of the disease and to determine the prognosis, easily to obtain with minimum discomfort or risk to the patient - exhaled breath analysis, blood cells and serum biomarkers, sputum cells and mediators and urine metabolites could be potential biomarkers of asthma bronchiale. Unfortunately, at the moment, an ideal biomarker doesn’t exist and the overlap between the biomarkers is a reality. Using panels of biomarkers could improve probably the identification of asthma endotypes in the era of precision medicine.

 Fuente / Autor
Kunc, P., Fabry, J., Lucanska, M., & Pecova, R. (2020). Biomarkers of Bronchial Asthma. En Physiological Research (pp. S29–S34). Institute of Physiology of the Czech Academy of Sciences. https://doi.org/10.33549/physiolres.934398